منابع مشابه
I-3: Hypogonadotropic Hypogonadism
Hypogonadotropic hypogonadism (HH) is an uncommon cause of male infertility and a congenital or secondary disorder characterized by delayed or absent sexual maturation. Congenital abnormalities leading to HH are usually the consequence of deficient GnRH secretion occurring either in isolation (idiopathic hypogonadotropic hypogonadism (IHH)), or in association with anosmia (Kallmann syndrome; KS...
متن کاملOutcomes of Prostate Biopsy in Men with Hypogonadism Prior or During Testosterone Replacement Therapy
INTRODUCTION The relationship between Testosterone Replacement Therapy (TRT) and prostate cancer remains controversial. Most TRT studies show no change in prostate specific antigen (PSA) but some men do have PSA rise or develop an abnormal digital rectal exam (aDRE). Our objective was to examine the biopsy results of men with symptomatic hypogonadism before or during therapy. MATERIALS AND ME...
متن کاملChallenges to treat hypogonadism in prostate cancer patients: implications for endocrinologists, urologists and radiotherapists
The literature suggests that the serum testosterone level required for maximum androgen receptor (AR) binding may be in the range of nanomolar and above this range of concentrations; this sexual hormone may not significantly affect tumour biology. This assumption is supported by clinical studies showing that cell proliferation markers did not change when serum T levels increased after exogenous...
متن کامل[Prolonged hypogonadism after cessation of androgen deprivation therapy for prostate cancer].
OBJECTIVES To study the levels of LH, testosterone and PSA after suspending prolonged treatment with LH-RH analogs. MATERIALS AND METHOD Hormonal evolution was studied in 29 patients from whom treatment had been withdrawn. The patients had previously been receiving treatment with LH-RH analog for more than one year, and with LH< 2 mUI/mL and testosterone < 2.8 ng/mL. LH, testosterone and PSA ...
متن کاملBone Mineral Density in Prostate Cancer Patients with Drug Induced Hypogonadism
Bone loss in patients with prostate cancer undergoing anti-androgen therapy is underestimated by physicians. Osteoporosis is a silent condition that can lead to major fracture events. The osteoporosis’s fractures has as consequence a decrease in a patient’s general health and quality of life, an increase in morbidity and mortality, and an increase in the cost to the health care system. The appl...
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ژورنال
عنوان ژورنال: Andrology
سال: 2020
ISSN: 2047-2919,2047-2927
DOI: 10.1111/andr.12772